Research platform
In order to stimulate clinical and translational research in Health, the Caen Normandy University Hospital has created within the new Biology Research Building a Research area of more than 600 m² where various research laboratories specializing in Health from the Caen site will now be located.
This research area will be ideally located near the various platforms of the Medical Biology Laboratory and the Research and Innovation Department of the University Hospital. It will facilitate interactions between researchers and clinicians, stimulate transdisciplinary exchanges, and welcome students and researchers in facilities dedicated to research and innovation.
Three strategic axes
The BB@C Institute is a GIS , founded by Inserm, the University of Caen Normandy and the Caen Normandy University Hospital, which brings together basic researchers, clinicians and entrepreneurs in a common goal of improving human health in neurology.
BB@C creates the tools for research excellence in Normandy, visible and attractive.
The emerging team “oncoCARE: Oncogenesis, Biomarkers and Therapeutic Targets of Solid Cancers and Malignant Hematological Diseases” will be attached to theISTCT Unit (Imaging and Therapeutic Strategies for Cancers and Brain Tissues_UMR6030) and theANTICIPE Unit. OncoCARE brings together researchers and clinicians from the Caen University Hospital whose focus is the dissection of the mechanisms of malignant transformation, the search for biomarkers and new therapeutic targets with the aim of continuously improving the care of patients with solid tumors (lung cancer, kidney cancer, gliomas) or malignant hematological diseases (lymphomas, mastocytosis and hypereosinophilia).
TheUMR 1311 INSERM DYNAMICURE (Microbial Dynamics associated with Urinary and Respiratory Infections). The DYNAMICURE unit is a research unit focused on the evolutionary dynamics of urinary and respiratory microbial agents (bacteria and viruses) , including their interactions with microbiomes, and the phenomena of persistence and emergence (epidemics, antimicrobial resistance).
Three transverse structures supporting these axes
The InnovaSEQ · Cell sorting and NGS platform @ Caen-Normandie is an innovative, non-thematic technological platform accessible to the entire scientific community. It offers equipment and services for flow cytometry, cell sorting, and high-throughput sequencing within the framework of research projects.
The platform provides equipment after user training and authorization and offers support in all stages of high-throughput functional genomics scientific projects in the form of research collaborations and/or services.
A shared space dedicated to innovative molecular biology tools is available to several organizations: BB@C, BioTARGen , and other potentially interested partners. The BioTARGen unit, in conjunction with the Rare Disease Reference Center for "Phosphocalcic Metabolism Anomalies," develops variant validation analyses (functionality tests) using transcriptomics or protein analysis (within the University Hospital G4 Genomics. The InnovaSEQ platform, offering flow cytometry, cell sorting, and high-throughput sequencing, hosted at the Caen University Hospital, is one of the building blocks implemented by the BB@C for the future.
Finally, a dedicated 3D printing area, bringing together several printers, will be identified at the heart of this space.