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Reproductive biology
Reproductive biology

Reproductive biology

Reproductive biology

Reproductive biology encompasses diagnostic activities in sperm analysis and therapeutic activities in Assisted Reproductive Technology (ART). The department provides care for patients seeking sperm donation, egg donation, double gamete donation, or embryo adoption.

Reproductive biology encompasses diagnostic activities in sperm analysis and therapeutic activities in Assisted Reproductive Technology (ART). The department provides care for patients seeking sperm donation, egg donation, double gamete donation, or embryo adoption.

Consultations & Team

Spermiology · CECOS

Dr Amélie Ancelle, Dr Marie-Ange Clarotti, Dr Antoine Clergeau, Dr Pauline Lechevallier

Andrology

Dr. Antoine Clergeau
Consultation hours

In Vitro Fertilization · Medically Assisted Reproduction

Dr Amélie Ancelle, Dr Marie-Ange Clarotti, Dr Antoine Clergeau, Dr Anne-Sophie Gille, Dr Pauline Lechevallier

Psychology

Ms Sandrine Hamonou, Ms Sabrina Launay
Consultation hours

    Service composition

    • 4 hospital practitioners
    • 1 attached practitioner
    • 2 psychologists
    • 1 healthcare manager
    • 7 laboratory technicians
    Team details

    Our services

    Activities

    The management of infertile couples requires close coordination between gynecological clinicians and biologists in Assisted Reproductive Technology (ART).

    These activities include biological, diagnostic and therapeutic activities within the Reproductive Biology sector of the medical biology laboratory.

    Diagnostic activities
    • Spermogram,
    • Sperm cytogram
    • Migration-survival test,
    • Seminal biochemistry,
    • Testing for anti-sperm antibodies,
    • Sperm DNA fragmentation
    Therapeutic activities
    • Intrauterine Insemination (IUI)
    • In Vitro Fertilization (IVF),
    • In vitro fertilization with intracytoplasmic sperm injection (ICSI).
    Other activities

    In collaboration with the urology department, we provide testicular sperm extraction (TESE) during surgical testicular biopsies, particularly in cases of azoospermia.

    The service takes care of donors and recipients of gamete donations (sperm and oocytes) and of embryo adoption.

    Finally, we also perform gamete, ovarian, and testicular tissue cryopreservation for fertility preservation before treatments that risk causing infertility in adults and children. Gamete cryopreservation is also possible without a medical indication for women aged 29 to 37 and men aged 29 to 45.

    The specific equipment of the service
    • Cultural items,
    • Laminar flow hoods,
    • Thermostatically controlled CO2 and tri-gas chambers
    • Micro-injection device,
    • Upright and inverted microscopes,
    • Automated freezing system for gametes and germinal tissues
    • Liquid nitrogen storage containers at -196 °C.

    Assisted Reproductive Technology (ART) and Fertility Preservation

    In humans

    Sperm cryopreservation is recommended before any treatment that could temporarily or permanently impair male fertility. Semen collection via masturbation is the first-line option. In some cases, surgical retrieval via testicular biopsy is also possible.

    Sperm are stored in liquid nitrogen at -196°C and can be stored indefinitely up to the age of 60, the maximum age allowed by law to use these gametes in the context of Assisted Reproductive Technology.

    Fertility preservation is indicated in various medical situations, including conditions such as cancer, inflammatory or hematological diseases, surgical procedures that may impair sexual or reproductive function, or as part of a gender transition. It is also possible, without a medical indication, for women aged 29 to 45. In this case, the annual preservation costs are not covered by social security.

    In women

    Fertility preservation is recommended before any treatment that could lead to temporary or permanent impairment of a woman's fertility. Egg freezing via ovarian puncture after ovarian stimulation treatment is the standard technique. In some cases, surgical removal of ovarian tissue for preservation is also possible.

    Oocytes or ovarian tissue are stored in liquid nitrogen at -196°C and can be stored indefinitely up to the age of 45, the maximum age allowed by law for use in Assisted Reproductive Technology or autologous transplantation.

    Fertility preservation is indicated in various medical situations, including conditions such as cancer, inflammatory or hematological diseases, ovarian surgery that may impair reproductive function, or as part of a gender transition. It is also possible, without a medical indication, for women aged 29 to 37. In this case, the annual preservation costs are not covered by social security.

    In children

    Fertility preservation is also possible in children in the context of certain pathologies.

    Before puberty , boys do not produce sperm. Testicular tissue cryopreservation is possible before treatment that carries a high risk of causing permanent sterility, but no technique is currently available to allow the use of this tissue. In adolescents , cryopreservation of ejaculated or surgically retrieved sperm is a possibility, depending on the stage of puberty and the boy's maturity.

    In girls before puberty, ovarian tissue cryopreservation is possible before high-risk treatments that could lead to permanent sterility, with a view to a transplant . In adolescent girls, the freezing of ovarian tissue or oocytes by ovarian puncture after ovarian stimulation treatment is discussed on a case-by-case basis, depending on the pathologies, age, and maturity of the girl.

    The Assisted Reproductive Technology Center

    Publications

    AMP Guide

    the guide to medically assisted reproduction

    Vasectomy

    Preserve your fertility before surgical sterilization

    Cystic fibrosis and fertility

    Transgender Identities – Fertility Preservation

      Gamete and embryo donation

      Medical biology laboratory

      Medical biology laboratory

      The directory of medical biology analyses at the Caen Normandy University Hospital is available here.

      Locate / contact the service

      Reproductive biology

      Women's and Children's Hospital - Hematology

      Avenue de la Côte de Nacre CS 30001 14033 Caen cedex 9

      Reproductive biology

      Secretariat of the department

      8am › 4pm

      LevelGPS accessParkingEntrance
      Spermiology · CECOS · Andrology
      Women's and Children's Hospital Hematology
      Level : 2
      GPS access: Main
      Parking: Parking 1
      Main entrance of the Caen Normandy University Hospital
      Assisted reproductive technology · In Vitro Fertilization
      Women's and Children's Hospital Hematology
      Level : 2
      GPS access: Main
      Parking: Parking 1
      Main entrance of the Caen Normandy University Hospital