The CHU Caen Normandie hosts two INSERM :
U1086 ANTICIPE and UMR 1311 DYNAMICURE .
The CHU also hosts the BB@C .
The Anticipation Unit develops basic and applied research aimed at proposing prevention or treatment strategies for cancer that are most suited to individuals and their environment. It brings together around a hundred people who develop research work structured around two axes: “Cancers and Prevention” and “Innovative Biology and Therapies of Ovarian Cancers” . It is coordinated by Professor Guy Launoy .
The multidisciplinary work is based on various tools (cohorts, cancer registers, Biological Resource Center and methodological and technological platforms) and aims to improve the prevention of cancers in agricultural environments, the organization of colon cancer screening -rectum and breast, the prevention of cognitive disorders in the treatment of cancers, and the therapeutic management of women with ovarian cancer resistant to chemotherapy. This work also proposes the implementation of programs aimed at reducing social and territorial inequalities in the prevention and treatment of cancer.
Labeled in January 2022, UMR 1311 DYNAMICURE is a two-site mono-team (CHU of Caen and Rouen) whose research theme is centered on the genomic evolution of microorganisms and their interactions with microbiomes. It brings together university hospital researchers from Caen and Rouen working in disciplines related to infectiology, including pediatrics and the study of pathogens. It is directed by Pr. Olivier Join-Lambert on the Caen site.
The unit's two research areas are viral respiratory infections and urinary tract infections. Bacteriology and Virology departments of the University Hospitals of Caen and Rouen, valued and developed within the Norman Federation Microbiology Hygiene ( FéNoMIH ).
The fundamental research themes developed concern more particularly:
- adaptation of microbial agents to the host and their environment, including antibiotic resistance, persistence
- the evolutionary and ecological dynamics associated with infection, epidemic circulation and the emergence of new pathogens
They are based on metagenomics and genomics approaches to holistically understand the interaction of pathogens with their environment, their genomic evolution and adaptation mechanisms.
The Blood and Brain @ Caen Normandie ( BB@C ) is a Scientific Interest Group, founded by Inserm, the University of Caen Normandie and the CHU Caen Normandie, which brings together fundamental researchers, clinicians and entrepreneurs to optimize and strengthen research and innovation in the field of Blood and Brain interactions. Particular emphasis is placed on neurovascular disorders (cerebrovascular accidents) , a major public health problem in the world and a strategic axis of the Caennais-Normand site with a thematic variation in the fields of neuro-inflammation, cerebral aging and psychiatry.
BB@C institute aims to offer support for emerging and innovative projects and to make resources available to respond to national and international calls for projects. These two levers must have a "transforming" effect and lead to better visibility and international attractiveness.
One of the major objectives is to structure in a sustainable way an institute where themes and research teams can be developed for the future (Teams labeled EPST - INSERM /UniCaen) .
BB@C is organized around an unprecedented transversal partnership involving academic research structures (laboratories and platforms) , a university hospital center (CHU) , companies and civil society. All contribute through their particular expertise, established individually, to achieve collective objectives.
Thus the excellence and complementarity of the consortium make it possible to claim to be a reference structure in Europe, visible and attractive, for designing, conducting and promoting translational research on Blood and Brain interactions.