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Inserm
Caen Normandy University Hospital

The certified units

The Caen Normandy University Hospital houses within it two INSERM- :
U1086 ANTICIPE and UMR 1311 DYNAMICURE .

The university hospital also houses the BB@C .

The Anticipe Unit conducts fundamental and applied research aimed at developing cancer prevention and treatment strategies best suited to individuals and their environments. It brings together approximately one hundred people who conduct research structured around two main areas: "Cancer and Prevention" and "Biology and Innovative Therapies for Ovarian Cancer ." It is coordinated by Professor Guy Launoy .

Multidisciplinary research relies on various tools (cohorts, cancer registries, Biological Resource Centers, and methodological and technological platforms) and aims to improve cancer prevention in agricultural settings, the organization of colorectal and breast cancer screening, the prevention of cognitive impairment during cancer treatment, and the therapeutic management of women with chemotherapy-resistant ovarian cancer. This research also proposes the implementation of programs designed to reduce social and territorial inequalities in cancer prevention and treatment.

Established in January 2022, UMR 1311 DYNAMICURE is a single-team, two-site unit (University Hospitals of Caen and Rouen) whose research focuses on the genomic evolution of microorganisms and their interactions with microbiomes. It brings together hospital-based university researchers from Caen and Rouen working in disciplines related to infectious diseases, including pediatrics and the study of pathogens. It is headed by Professor Olivier Join-Lambert at the Caen site.

The unit's two research areas are respiratory viral infections and urinary tract infections. These themes are based on hospital clinical activities, from the Bacteriology and Virology of the University Hospitals of Caen and Rouen, which are promoted and developed within the Normandy Federation of Microbiology and Hygiene ( FéNoMIH ).

The fundamental research themes developed relate more specifically to:

  • the adaptation of microbial agents to the host and their environment, including antibiotic resistance, persistence
  • the evolutionary and ecological dynamics associated with infection, epidemic circulation, and the emergence of new pathogens

They are based on metagenomics and genomics approaches that allow for a holistic understanding of the interaction of pathogens with their environment, their genomic evolution and adaptation mechanisms.

BB@C

The Blood and Brain @ Caen Normandy ( BB@C ) Institute is a Scientific Interest Group, founded by Inserm, the University of Caen Normandy, and the Caen Normandy University Hospital, which brings together basic researchers, clinicians, and entrepreneurs to optimize and strengthen research and innovation in the field of blood-brain interactions. Particular emphasis is placed on neurovascular disorders (strokes) , a major public health problem worldwide and a strategic focus for the Caen-Normandy region, with thematic extensions into the fields of neuroinflammation, brain aging, and psychiatry.

BB@C Institute aims to support emerging and innovative projects and provide resources to respond to national and international calls for proposals. These two levers should have a "transformative" effect and lead to greater international visibility and attractiveness.

One of the major objectives is to structure in a sustainable way an institute where research themes and teams can be developed for the future (Teams labeled EPST - INSERM /UniCaen) .

BB@C is organized around an unprecedented cross-sectoral partnership involving academic research structures (laboratories and platforms) , a university hospital (CHU) , businesses, and civil society. All contribute their specific, individually established expertise to achieving collective objectives.

Thus, the excellence and complementarity of the consortium allow it to claim to be a reference structure in Europe, visible and attractive, for designing, conducting and promoting translational research on Blood and Brain interactions.