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Biological hematology
Biological hematology

Biological hematology

Biological hematology

The biological hematology laboratory has three missions. Ensure, in the field of hematology, the diagnosis and biological follow-up of patients hospitalized or not at the CHU, provide all those who wish it with high quality training in hematology, and develop research programs in hematology.

The biological hematology laboratory has three missions. Ensure, in the field of hematology, the diagnosis and biological follow-up of patients hospitalized or not at the CHU, provide all those who wish it with high quality training in hematology, and develop research programs in hematology.

  • Consultations Consultations Consultations Consultations

    Thrombosis assessment

    Dr Benjamin Gillet
    Consultation schedule

    Haemophilia

    Pr Yohann Repesse, Dr Benjamin Gillet
    Consultation schedule

    Hemorrhagic assessment

    Pr Yohann Repesse, Dr Benjamin Gillet
    Consultation schedule

    Willebrand disease

    Pr Yohann Repesse, Dr Benjamin Gillet
    Consultation schedule

      Composition of service

      • 1 University Professor · Hospital Practitioner
      • 1 University Hospital Practitioner
      • 6 Hospital Practitioners
      • 3 Attached Practitioners
      • 1 Senior Health Officer
      • 1 Health Executive
      • 1 medico-administrative assistant
    • Activities

      Routine activities

      They are quantitatively the most important and correspond to the realization of blood counts, leucocyte formulas and hemostasis tests necessary for the follow-up of patients hospitalized and cared for in the Department of Reception and Emergency Treatment.

      Specialized activities
      Cellular hematology

      Cellular hematology corresponds to the biological activities required for the diagnosis and biological monitoring of patients with leukemia and cancer:

      • hemograms or blood counts, platelets and white blood cell counts,
      • cytological study of myelograms, adenograms, bone marrow biopsies and puncture fluids,
      • diagnosis of malignant hemopathies by cytological study, immunophenotyping by flow cytometry, search for fusion transcripts by molecular biology, study of chromosomal abnormalities by interphase FISH,
      • follow-up of these pathologies,
      • study of constitutional abnormalities of the red blood cell.
      Hemostasis

      Hemostasis corresponds to the biological activities required for the diagnosis and biological follow-up of patients with a constitutional hemorrhagic disease (hemophilia, Willebrand's disease) or a thrombotic disease.
      A haemostasis consultation, provided by the doctors of the laboratory, makes it possible to carry out on the spot the blood sample necessary for a specialized exploration and adapted to the diagnosis and therapeutic advice:

      • diagnosis, including molecular, of thrombophilias,
      • phenotypic characterization of Willebrand's disease with the diagnosis of the different subtypes and the appropriate therapeutic choices,
      • diagnosis of heparin-induced thrombocytopenia: performance of the various tests,
      • molecular diagnosis of hemophilia A with sequencing of the F VIII gene.

      All these cellular hematology and hemostasis activities ensure a mission of regional expertise in diagnostic assistance, advice and the standardization of methodologies with collaborations between the clinical departments and the laboratories of general hospitals and the private laboratories.

      Teaching activities

      They are part of the LMD reform and are essential for the training of biologists in the Basse-Normandie region and also concern:

      • hematology training for medical and pharmacy students,
      • the training of interns in biology,
      • the training of students, trainees BTS or equivalent, DUT.
    • Reference centers & collaborations

    • The research

      Cellular hematology

      Conducted in parallel with hospital activities, research activities focus on understanding the mechanisms of leukemia and cancer and on improving patient care.

      • MICAH research group depends on the UFR Santé of the University of Caen Normandy. It is under a partnership contract with INSERM and the University of Rouen Normandy. MICAH research group is part of team 2 Genomics and Biomarkers of Lymphoma and Solid Tumors led by Fabrice Jardin, which is one of the five constituent research teams of INSERM unit U1245 ( Cancer and brain genomics, CBG) directed by Gael Nicolas . He has been studying the pathophysiology of hematological malignancies for many years. Its main theme is to understand which cellular dysfunctions contribute to the development of cancers affecting B lymphocytes and the mechanisms of resistance to treatment. He studies rare pathologies such as hairy cell leukemia, primary lymphoma of the mediastinum, Hodgkin's lymphoma and Mantle cell lymphoma.
      • Biological Resource Center: collection of biological materials of human origin
      • Regional Register of Malignant Hemopathies of Basse-Normandie.

      Hemostasis

      • Validation of biological tests
      • Basic research with a connection with the INSERM U1237 team, PhIND “Physiopathology and Imaging of Neurological Disorders” team: evaluation of predictive biomarkers of fibrinolysis success, Willebrand disease type 2B and cerebral pathologies, Tolerance to factor VIII (FVIII) in severe hemophilia A patients.
      • Clinical research activities (phase 2, 3 and 4 clinical trials).
    • The latest news related to the service…

    Medical biology laboratory

    Medical biology laboratory

    The directory of medical biology analyzes of the CHU Caen Normandie is available here.

    Locate / contact service

    Biological hematology

    Building Biology Research

    Avenue de la Côte de Nacre
    CS 30001
    14033 Caen cedex 9


    Biological hematology

    Service Secretariat


    Level GPS accessHall
    Biological hematology
    Building Biology Research
    Level: Ground floor
    GPS Access: BBR Logistics
    Biology Research Building